This course closed on Sunday, November 20, 2022

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Good, Better, Best: The Role of L-Methylfolate in Today’s Psychiatric/Clinical Practice

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FACULTY

Rakesh Jain, MD
Clinical Professor
Texas Tech - Permian Basin

Gustavo Alva, MD
Medical Director, ATP Clinical Research
 

PROVIDER STATEMENT

Provided by HMP Education, an HMP Global Company.

For questions regarding this educational activity, please call 609-371-1137 or email accreditation@hmpglobal.com.

INTENDED LEARNERS

This activity is intended for psychiatrists, primary care physicians, psychologists, nurse practitioners, physician assistants, psychiatric nurses, and other healthcare professionals who seek to improve the care of patients with mental health disorders.

LEARNING OBJECTIVES

After participating in this activity, learners should be better able to:

  • Describe the limitations of traditional monoaminergic antidepressants in patients with depression, including suboptimal response and remission rates
  • Discuss the neurobiological role/MOA of L-methylfolate in depression and potential clinical implications
  • Assess safety and efficacy data associated with the use of L-methylfolate as an adjunctive therapy to currently available antidepressant agents
  • Employ treatment strategies with L-methylfolate according to specific patient profiles for improved outcomes in major depression

CLAIMING CREDIT

To be eligible for credit, participants must complete the online activity and the evaluation. Upon completing the activity, there will be instructions on how to complete the evaluation and print a certificate or other documentation of credit.

Release Date: September 20, 2022
Expiration Date: November 19, 2022
Estimated Time to Complete: 75 minutes

There is no fee associated with this activity.

CONTINUING EDUCATION

In support of improving patient care, HMP Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

 

PHYSICIANS

HMP Education designates this internet live activity for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

NURSES

This continuing nursing education internet live activity awards 1.25 contact hour.

Provider approved by the California Board of Registered Nursing, Provider #13255 for 1.25 contact hour. 

NURSE PRACTITIONERS

American Academy of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 CreditTM from organizations accredited by the ACCME.

PHYSICIAN ASSISTANTS

HMP Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with the AAPA CME Criteria. This internet live activity is designated for 1.25 AAPA Category 1 credits. PAs should only claim credit commensurate with the extent of their participation.

PSYCHOLOGISTS

APA Logo Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs.

SOCIAL WORKERS

As a Jointly Accredited Organization, HMP Education is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit. Social workers completing this course receive 1.25 general continuing education credits.

MARRIAGE & FAMILY THERAPISTS

As a Jointly Accredited Organization, HMP Education is approved by the American Psychological Association to sponsor continuing education for psychologists. The APA pre-approves New Jersey, Connecticut, Delaware, Rhode Island, South Dakota and Washington D.C., for Marriage and Family Therapy credit. HMP Education has received pre-approval for this conference from the following marriage and family boards:

HMP Education has received additional pre-approval for this conference from the following marriage and family boards: California.

USE OF PROPRIETARY NAMES

This continuing medical education activity may include device or medicine brand names for participant clarity purposes only, due to the presence of different branded versions of the same product. No product promotion or recommendation should be inferred.

UNAPPROVED AND/OR INVESTIGATIONAL USES OF DRUGS AND DEVICES

This activity may contain information about experimental and other uses of drugs or devices that are not currently approved by the European Medicines Agency (EMA) of the European Union or the Food and Drug Administration (FDA) of the United States. Participants are strongly encouraged to consult approved product labeling for any drug or device mentioned in this activity before use. The opinions expressed during this activity are the opinions of the respective authors, presenters or moderators and do not necessarily reflect the opinions of HMP Education.

DISCLAIMERS

The material presented and related discussions are not intended to be medical advice, and the presentation or discussion of such material is not intended to create and does not establish a physician-patient relationship. Medical advice of any nature should be sought from an individual’s own physician.

Neither HMP Education nor any of its subsidiaries or affiliates is affiliated with, or formally endorsed by a medical society.

The opinions expressed in this educational activity are those of the faculty and are not attributable to HMP Education or HMP. Clinical judgment must guide each professional in weighing the benefits of treatment against the risk of toxicity. Dosages, indications, and methods of use for products referred to in this activity are not necessarily the same as indicated in the package insert for each product, may reflect the clinical experience of the presenters, and may be derived from the professional literature or other clinical sources. Consult complete prescribing information before administering.

DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS

HMP Education is an independent provider of continuing medical education. HMP Education has no proprietary or financial interest in medical or healthcare products over which the FDA (USA) or EMA (EU) has regulatory authority.

In accordance with our disclosure policies, HMP Education is committed to ensuring balance, independence, objectivity, and scientific rigor for all accredited continuing education. These policies include assigning relevance to, and mitigating, all perceived or real conflicts of interest between any individual with control over the content and any ineligible company (commercial interest) as defined by the ACCME.

Any individual with control over accredited content, including planner, faculty, and reviewer, is required to globally disclose:

  1. Individual relationship(s) or lack thereof, and its nature, with any/all ineligible company, and;
  2. Any investigational, off-label, or non-FDA approved content or discussion

HMP Education has reviewed these disclosures, assigned relevance based on the relationship and scope of content, and identified those with the potential to compromise the goals and educational integrity of the education. Relevant relationships, or lack thereof, are shared with the learner.

Education has been independently peer-reviewed to validate content, mitigate identified conflicts of interest, and ensure:

  1. All recommendations involving clinical medicine is based on evidence that is accepted within the medical profession as adequate justification for their indications and contraindications in the care of patients.
  2. All scientific research referred to, reported, or used in accredited continuing education in support or justification of a patient care recommendation conforms to the generally accepted standards of experimental design, data collection, and analysis.
  3. Content is appropriate, fair and balanced, unbiased, referenced, and non-promotional.

FACULTY

The faculty has reported the following:

Dr. Alva: Advisory Board—AbbVie, Abbott, Acadia, Alkermes, Allergan, Amgen, Avanir, Biogen, Celgene, Cerevel Therapeutics, Cubist, Eisai, Ferring, Genentech, Janssen, Intra-Cellular Therapies, Inc., Liva Nova, Lundbeck, Merck, Myriad, Neurocrine Biosciences, Inc., Otsuka America Pharmaceutical, Inc., Sage Therapeutics, Shire, Elan, GlaxoSmithKline, Hospira, Pfizer, Bristol-Myers Squibb, Roche, Salix, Seattle Genetics, Takeda, Teva Pharmaceuticals; Consultant—AbbVie, Abbott, Acadia, Alkermes, Allergan, Amgen, Avanir, Biogen, Celgene, Cerevel Therapeutics, Cubist, Eisai, Ferring, Genentech, Janssen, Intra-Cellular Therapies, Inc., Liva Nova, Lundbeck, Merck, Myriad, Neurocrine Biosciences, Inc., Otsuka America Pharmaceutical, Inc., Sage Therapeutics, Shire, Elan, GlaxoSmithKline, Hospira, Pfizer, Bristol-Myers Squibb, Roche, Salix, Seattle Genetics, Takeda, Teva Pharmaceuticals; Grant/Research Support—AbbVie, Abbott, Acadia, Alkermes, Allergan, Amgen, Avanir, Biogen, Celgene, Cerevel Therapeutics, Cubist, Eisai, Ferring, Genentech, Janssen, Intra-Cellular Therapies, Inc., Liva Nova, Lundbeck, Merck, Myriad, Neurocrine Biosciences, Inc., Otsuka America Pharmaceutical, Inc., Sage Therapeutics, Shire, Elan, GlaxoSmithKline, Hospira, Pfizer, Bristol-Myers Squibb, Roche, Salix, Seattle Genetics, Takeda, Teva Pharmaceuticals; Speakers Bureau—AbbVie, Abbott, Acadia, Alkermes, Allergan, Amgen, Avanir, Biogen, Celgene, Cerevel Therapeutics, Cubist, Eisai, Ferring, Genentech, Janssen, Intra-Cellular Therapies, Inc., Liva Nova, Lundbeck, Merck, Myriad, Neurocrine Biosciences, Inc., Otsuka America Pharmaceutical, Inc., Sage Therapeutics, Shire, Elan, GlaxoSmithKline, Hospira, Pfizer, Bristol-Myers Squibb, Roche, Salix, Seattle Genetics, Takeda, Teva Pharmaceuticals

Dr. Jain: Advisory Board—Adamas, Alkermes, Corium, Eisai, Indivior, Intra-Cellular Therapies, Ironshore Pharmaceuticals, Janssen, Lilly, Lundbeck, Merck, Neos Therapeutics, Neurocrine Biosciences, Otsuka, Pamlab, Pfizer, Shire, Sunovion, Supernus, Takeda, Teva, Tris Pharmaceuticals; Advisory Board (spouse)—Otsuka; Consultant—AbbVie (Allergan), Acadia, Adamas, Alfasigma USA, Inc., Axsome, Corium, Cingulate Therapeutics, Eisai, Evidera, Impel NeuroPharma, Janssen, Lilly, Lundbeck, Merck, Neos Therapeutics, Neurocrine Biosciences, Osmotica, Otsuka, Pamlab, Pfizer, Sage Therapeutics, Shire, Sunovion, Supernus, Takeda, Teva; Consultant (spouse)—Lilly, Otsuka, Pamlab, Sunovion; Grant/Research Support— AbbVie (Allergan), Lilly, Lundbeck, Otsuka, Pfizer, Shire, Takeda; Speakers Bureau—AbbVie (Allergan), Alkermes, Axsome, Corium, Eisai, Indivior, Intracellular Therapies, Ironshore Pharmaceuticals, Janssen, Lilly, Lundbeck, Merck, Neos Therapeutics, Neurocrine, Otsuka, Pamlab, Pfizer, Shire, Sunovion, Takeda, Teva, Tris Pharmaceuticals; Speakers Bureau (Spouse)—Lilly.

 

CLINICAL REVIEWER

Douglas Noordsy, MD
Clinical Professor Director of Lifestyle Psychiatry
Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine
Palo Alto, California

William C. Torrey, MD
Professor and Vice Chair for Clinical Services
Dartmouth’s Geisel School of Medicine, Dartmouth-Hitchcock
Lebanon, New Hampshire

Dr. Noordsy and Dr. Torrey have disclosed no relevant financial relationship with any ineligible company (commercial interest).

PLANNING COMMITTEE

Susie Seaman, NP, MSN, CWOCN (nurse planner)
Wound Clinics, Family Health Centers of San Diego
San Diego, California

Ms. Seaman has disclosed no relevant financial relationship with any ineligible company (commercial interest).

HMP Education planners and staff include Samantha Conforti, Randy Robbin, and Andrea Zimmerman.

No HMP Education planner or staff has disclosed a relevant financial relationship with any ineligible company (commercial interest).

ADA STATEMENT

HMP Education complies with the legal requirements of the Americans with Disabilities Act and the rules and regulations thereof. If any participant in this educational activity is in need of accommodations, please call 609-371-1137.

PRIVACY POLICY

HMP Education protects the privacy of personal and other information regarding participants, educational partners, and joint providers. HMP Education and our joint providers will not release personally identifiable information to a third party without the individual’s consent, except such information as is required for reporting purposes to the appropriate accrediting agency. HMP Education maintains physical, electronic, and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Copyright © 2022 by HMP Education. All rights reserved. No part of this accredited continuing education activity may be reproduced or transmitted in any form or by any means, electronic or mechanical, without first obtaining permission from HMP Education.

GRIEVANCE POLICY

Any participant wanting to file a grievance with respect to any aspect of a continuing education activity accredited by HMP Education may contact Samantha Conforti, Senior Manager, Accreditation and Compliance, by phone at 609-371-1137, by email at sconforti@hmpglobal.com or in writing at 104 Windsor Center Drive, East Windsor, NJ 08520. Ms. Conforti will review the grievance and respond within 30 days of receiving the complaint.

Commercial Support

The following companies have provided an educational grant in support of this activity: Alfasigma USA, Inc.