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New Treatment Paradigm for Venous and Arterial Disease: The Multidisciplinary Approach and the Role of DOACs


Marc Bonaca, MD
University of Colorado Anschutz Medical Campus
Aurora, Colorado

Ian Del Conde, MD
Miami Cardiac & Vascular Institute
Miami, Florida

William Gray, MD
Main Line Health

Vamsi Krishna, MD
Seton Heart Institute
Kyle, Texas

Fadi Saab, MD
Advanced Cardiac & Vascular Centers for Amputation Prevention
Grand Rapids, Michigan


Provided by HMP Education, an HMP Global Company.

For questions regarding this educational activity, please call 609-371-1137 or email


This activity is designed for interventional radiologists, vascular surgeons, interventional cardiologists, interventional neuroradiologists, cardiothoracic surgeons, clinical cardiologists, clinical radiologists, neurologists, internists, nurses, and others involved in the treatment of cardiovascular disease.


After participating in this activity, learners should be better able to:

  • Describe the epidemiology and disease burden of venous and arterial diseases.
  • Compare and contrast the mechanisms of action of conventional vitamin K antagonist (VKA) therapies and newer direct oral anticoagulants (DOAC).
  • Evaluate safety, efficacy, and indications for DOACs in the management of VTE and PAD.
  • Incorporate evidence-based current guidelines into clinical protocols for the optimal management of VTE and PAD.


To be eligible for credit, participants must complete the online activity and the evaluation. Upon completing the activity, there will be instructions on how to complete the evaluation and print a certificate or other documentation of credit.

Release Date: February 4, 2022
Expiration Date: February 4, 2023
Estimated Time to Complete: 1 hour

There is no fee associated with this activity.


In support of improving patient care, HMP Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


HMP Education designates this internet enduring activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


This continuing nursing education internet enduring activity awards 1 contact hour.

Provider approved by the California Board of Registered Nursing, Provider #13255 for 1 contact hour. 


American Academy of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 CreditTM from organizations accredited by the ACCME.


HMP Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with the AAPA CME Criteria. This internet enduring activity is designated for 1 AAPA Category 1 credit. PAs should only claim credit commensurate with the extent of their participation.


New Treatment Paradigm for Venous and Arterial Disease: The Multidisciplinary Approach and the Role of DOACs taking place on 1/17/22 from 7:00 - 8:00 AM has been submitted for 1 A+ ARRT CE credits by the Association for Vascular and Interventional Radiographers (AVIR). The AVIR is an ARRT Recognized Continuing Education Evaluating Mechanism, (RCEEM).


This continuing medical education activity may include device or medicine brand names for participant clarity purposes only, due to the presence of different branded versions of the same product. No product promotion or recommendation should be inferred.


This activity may contain information about experimental and other uses of drugs or devices that are not currently approved by the European Medicines Agency (EMA) of the European Union or the Food and Drug Administration (FDA) of the United States. Participants are strongly encouraged to consult approved product labeling for any drug or device mentioned in this activity before use. The opinions expressed during this activity are the opinions of the respective authors, presenters or moderators and do not necessarily reflect the opinions of HMP Education.


The material presented and related discussions are not intended to be medical advice, and the presentation or discussion of such material is not intended to create and does not establish a physician-patient relationship. Medical advice of any nature should be sought from an individual’s own physician.

Neither HMP Education nor any of its subsidiaries or affiliates is affiliated with, or formally endorsed by a medical society.

The opinions expressed in this educational activity are those of the faculty and are not attributable to HMP Education or HMP. Clinical judgment must guide each professional in weighing the benefits of treatment against the risk of toxicity. Dosages, indications, and methods of use for products referred to in this activity are not necessarily the same as indicated in the package insert for each product, may reflect the clinical experience of the presenters, and may be derived from the professional literature or other clinical sources. Consult complete prescribing information before administering.


HMP Education is an independent provider of continuing medical education. HMP Education has no proprietary or financial interest in medical or healthcare products over which the FDA (USA) or EMA (EU) has regulatory authority.

In accordance with our disclosure policies, HMP Education is committed to ensuring balance, independence, objectivity, and scientific rigor for all accredited continuing education. These policies include assigning relevance to, and mitigating, all perceived or real conflicts of interest between any individual with control over the content and any ineligible company (commercial interest) as defined by the ACCME.

Any individual with control over accredited content, including planner, faculty, and reviewer, is required to globally disclose:

  1. Individual relationship(s) or lack thereof, and its nature, with any/all ineligible company, and;
  2. Any investigational, off-label, or non-FDA approved content or discussion

HMP Education has reviewed these disclosures, assigned relevance based on the relationship and scope of content, and identified those with the potential to compromise the goals and educational integrity of the education. Relevant relationships, or lack thereof, are shared with the learner.

Education has been independently peer-reviewed to validate content, mitigate identified conflicts of interest, and ensure:

  1. All recommendations involving clinical medicine is based on evidence that is accepted within the medical profession as adequate justification for their indications and contraindications in the care of patients.
  2. All scientific research referred to, reported, or used in accredited continuing education in support or justification of a patient care recommendation conforms to the generally accepted standards of experimental design, data collection, and analysis.
  3. Content is appropriate, fair and balanced, unbiased, referenced, and non-promotional.


The faculty has reported the following:

Marc Bonaca, MD: Grant/Research Support - Abbott, Agios, Alexion Pharma, Alnylam, Amgen, Angionetics, ARCA Biopharma, Array, AstraZeneca, Atentiv, Audentes, Bayer, Better Therapeutics, Brigham and Women’s Hospital, Bristol-Myers Squibb, Cardiol Therapeutics, CellResearch, Cook Medical, Cook, CSL Behring, Eidos Therapeutics, EP Trading Co, Esperion Therapeutics, EverlyWell, Faraday, Fortress Biotech, HDL Therapeutics, Heartflow, Hummingbird Bioscience, Insmed, Janssen, Kowa Research, Lexicon, Merck, Medtronic, Moderna, Novate Medical, NovoNordisk, Pfizer, PhaseBio, PPD Development, Prairie Education and Research, Prothena Ciosciences, Regeneron, Regio Biosciences, Sanifit Therapeutics, Sanofi, Smith and Nephew, Stealth BioTherapeutics, University of Colorado, Worldwide Clinical Trials, Wraser, Yale Cardiovascular Research Group; Stocks -  Medtronic, Pfizer; Consultant – Audentes
Ian Del Conde, MD: Speakers Bureau – Abbott, Boston Scientific, Janssen, Pfizer
William Gray, MD: Abbott Vascular: Contracted Research, Other Financial or Material Support; Alucent: Consultant; Biocardia Inc: Other Financial or Material Support, Stocks; Boston Scientific Corporation: Consultant, Contracted Research; Edwards Lifesciences: Consultant, Contracted Research, Other Financial or Material Support, Other Financial or Material Support; GORE: Consultant, Contracted Research; Intact Vascular: Consultant; Mecator: Contracted Research, Other Financial or Material Support, Other Financial or Material Support; Medtronic: Consultant, Contracted Research, Other Financial or Material Support; Philips: Consultant, Contracted Research, Other Financial or Material Support, Other Financial or Material Support; SHOCKWAVE: Consultant, Contracted Research, Other Financial or Material Support, Other Financial or Material Support; Surmodics: Consultant 
Vamsi Krishna, MD: Ad Board – Abbott, AstraZeneca, Janssen, Philips, Terumo; Speaker – Abbott, Amgen, AstraZeneca, Flow Therapy, Janssen, Philips, Shockwave, Terumo; Research – AstraZeneca, Flow Therapy, Janssen, Philips, Terumo

Fadi Saab, MD: Consultant – BD, Boston Scientific, Cardiovascular Systems, Inc, Medtronic, Philips, Terumo; Grant/Research Support – Avinger, Boston Scientific, Cardio Flow, Micro Medical Solutions, Terumo; Equity Ownership – Cardio Flow


Adam Geronemus, MD, FSIR
Interventional Radiologist
Miami Cardiac & Vascular Institute
South Miami Heart Center
Miami, Florida

Brian Schiro, MD, RPVI, FSIR
Medical Director, Baptist & Doctors Hospital Noninvasive Vascular Lab
Program Directors, Independent Interventional Radiology Residency
Assistant Clinical Professor, University of South Florida, School of Medicine
Assistant Professor, Florida International University Herbert Wertheim College of Medicine
Miami, Florida

Adam Geronemus, MD, FSIR: Cordis - Consultant

Brian J. Schiro, MD - Medtronic: Speaker's Bureau, Speaker's Bureau; PENUMBRA INC: Speaker's Bureau, Speaker's Bureau; Philips Healthcare: Consultant, Speaker's Bureau; SIRTEX: Speaker's Bureau  


Susie Seaman, NP, MSN, CWOCN (nurse planner)
Susie Seaman Wound Care Consulting
San Diego, California

Ms. Seaman has disclosed no relevant financial relationship with any ineligible company (commercial interest).

HMP Education planners and staff include Samantha Conforti, Randy Robbin, and Greaton Sellers.

No HMP Education planner or staff has disclosed a relevant financial relationship with any ineligible company (commercial interest).


HMP Education complies with the legal requirements of the Americans with Disabilities Act and the rules and regulations thereof. If any participant in this educational activity is in need of accommodations, please call 609-371-1137.


HMP Education protects the privacy of personal and other information regarding participants, educational partners, and joint providers. HMP Education and our joint providers will not release personally identifiable information to a third party without the individual’s consent, except such information as is required for reporting purposes to the appropriate accrediting agency. HMP Education maintains physical, electronic, and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Copyright © 2022 by HMP Education. All rights reserved. No part of this accredited continuing education activity may be reproduced or transmitted in any form or by any means, electronic or mechanical, without first obtaining permission from HMP Education.


Any participant wanting to file a grievance with respect to any aspect of a continuing education activity accredited by HMP Education may contact Samantha Conforti, Manager, Accreditation and Compliance, by phone at 609-371-1137, by email at or in writing at 104 Windsor Center Drive, East Windsor, NJ 08520. Ms. Conforti will review the grievance and respond within 30 days of receiving the complaint. If the participant is unsatisfied with the response, an appeal to the Associate Director, Greaton Sellers,  Accreditation and Compliance, can be requested for a second level of review. Mr. Sellers can be contacted via phone at 609-371-1137, by email at or in writing at 104 Windsor Center Drive, East Windsor, NJ 08520.

Commercial Support

The following company has provided an educational grant in support of this activity: Janssen Scientific Affairs, LLC.