Immunotherapy-Based Combination Therapies in NSCLC: Addressing Treatment Resistance
Lyudmila Bazhenova, MD
Professor of Medicine
University of California, San Diego
Leena Gandhi, MD, PhD
Associate Professor of Medicine/Director, Center for Cancer Therapeutic Innovation
Harvard Medical School/Dana-Farber Cancer Institute
Marina Garassino, MD
Professor of Medicine
University of Chicago
Edward B. Garon, MD, MS
University of California, Los Angeles
Corey J. Langer, MD, FACP
Director of Thoracic Oncology
Abramson Cancer Center, Hospital of the University of Pennsylvania
Aaron Lisberg, MD
Assistant Professor of Medicine
University of California, Los Angeles
Karen Reckamp, MD
Cedars Sinai Medical Center
Helen J. Ross, MD
Thoracic Medical Oncologist
Banner MD Anderson Cancer Center
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This activity is designed to meet the educational needs of medical oncologists, nurses, nurse practitioners, physician assistants, pathologists, pulmonologists, oncology pharmacists, researchers, internists wishing to have an update on the diagnosis and management of lung cancer, and other healthcare professionals interested in the care and treatment of patients with thoracic malignancies.
After participating in this activity, learners should be better able to:
- Evaluate the rationale, mechanisms, and latest clinical data for current and emerging immune checkpoint inhibitor (ICI)-based combination therapies
- Utilize treatment selection and sequencing strategies to minimize treatment resistance
- Integrate adverse event management strategies to optimize time on treatment and mitigate treatment risks
This on-demand webcast is available with synchronized slides and video/audio.
To be eligible for credit, participants must complete the educational activity, complete the 5-question post-test with a minimum score of 70%, and complete the activity evaluation form. Upon completing the activity, there will be instructions on how to complete the evaluation and print a certificate or other documentation of credit.
Release Date: January 20, 2023
Expiration Date: January 20, 2024
Estimated Time to Complete: 2.75 hours
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The faculty has reported the following:
Lyudmila Bazhenova: Advisory Board - Boehringer Ingelheim, Bristol Meyer Squibb, Daiichi Sankyo, Janssen Biotech, Merck Serono, Novartis Pharmaceuticals, Turning Point Therapeutics; Consultant - Neuvogen
Leena Gandhi: Advisory Board - Beigene, BMS, Eisai, Mersana Therapeutics, Surface Oncology, Tentarix, Xilio; Consultant - 28-7 Therapeutics, Pliant Therapeutics; Board of Directors - Bright Peak Therapeutics, Neximmune
Marina Garassino: Personal Financial Interests - AstraZeneca, MSD International GmbH, BMS, Boehringer Ingelheim Italia S.p.A, Celgene, Eli Lilly, Incyte, Inivata, MedImmune, Novartis, Pfizer, Roche, Takeda, Seattle Genetics, Mirati, Daiichi Sankyo; Institutional Financial Interests - Eli Lilly, MSD, Pfizer (MISP), AstraZeneca, MSD International GmbH, BMS, Boehringer Ingelheim Italia S.p.A, Celgene, Eli Lilly, Ignyte, Incyte, MedImmune, Novartis, Pfizer, Roche, Takeda, Tiziana, Foundation Medicine, Glaxo Smith Kline GSK, Spectrum Pharmaceuticals; Research Fundings - AIRC, AIFA, Italian Moh, Transcan
Edward B. Garon: Advisory Board - ABL-Bio, AstraZeneca, Boehringer Ingelheim, Bristol Meyer Squibb, Eisai, Eli Lilly, EMD Serono, Gilead, GSK, Merck, Natera, Novartis, Personalis, Regeneron, Sanofi/Genzyme, Xilio, Zymeworks Biopharm; Grant/Research Support - ABL-Bio, AstraZeneca, Bristol Myer Squibb, Eli Lilly, EMD Serono, Genentech, Iovance, Merck, Mirati, Novartis
Corey J. Langer: Consultant - AstraZeneca; Grant/Research Support - Pfizer, Lilly, Advantagene, Inovio, Celgene, Vertex, Ariad (Takeda), Merck, Stemcentrex, Genentech/Roche, AstraZeneca, Trizell, GSK, Guardant; Other Material Support(Data Safety Monitoring) - Lilly, Amgen, Peregrine, Incyte, SWOG, Oncocyte; Advisory Board - Bristol Myers Squibb, Lilly, Pfizer, Synta, Boehringer-Ingelheim, AstraZeneca, Novartis, Abbott, Genentech/Roche, Savient, Bayer/Onyx, Celgene, Clarient, Clovis, Guardant, Merck, Gilead
Aaron Lisberg: Grant/Research Support - Daiichi Sankyo, Calithera Biosciences, AstraZeneca, Dracen Pharmaceuticals, WindMIL, eFFECTOR Therapeutics; Consultant/Advisory Board - AstraZeneca, Bristol-Myers Squibb, Leica Biosystems, Jazz Pharmaceuticals, Novocure, Pfizer, MorphoSys, Eli-Lilly, Oncocyte, Novartis, Regeneron, Janssen Oncology, Sanofi; Employment - Boston Scientific (Immediate Family Member); Stock - Boston Scientific (Immediate Family Member)
Karen Reckamp: Consultant - Amgen, AstraZeneca, Blueprint, Daiichi Sankyo, EMD Soreno, Genentech, GlaxoSmithKline, Janssen, Lilly, Merck KGA, Mirati, Seattle Genetics, Takeda, Tesaro
Helen J. Ross: Grant/Research Support/Funding for Alliance Foundation Trials - Roche Genentech
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Supported by independent educational grants from Eisai Co. and Merck & Co., Inc