New and Emerging ALK/ROS1/NTRK-Targeted Agents in NSCLC: Addressing Treatment Resistance and CNS Metastases
Edward B. Garon, MD, MS
University of California, Los Angeles
Corey J. Langer, MD, FACP
Director of Thoracic Oncology
Abramson Cancer Center, Hospital of the University of Pennsylvania
Jessica J. Lin, MD
Assistant Professor in Medicine
Harvard Medical School
Rajwanth Veluswamy, MD, MSCR
Icahn School of Medicine at Mount Sinai
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This activity is designed me toet the educational needs of medical oncologists, nurses, nurse practitioners, physician assistants, pathologists, pulmonologists, oncology pharmacists, researchers, internists wishing to have an update on the diagnosis and management of lung cancer, and other healthcare professionals interested in the care and treatment of patients with thoracic malignancies.
After participating in this activity, learners should be better able to:
- Assess guideline recommendations, testing techniques, and clinical applications for molecular profiling to identify patients who will benefit from ALK, ROS1, or NTRK-targeted therapy
- Evaluate clinical efficacy and safety data for new and emerging ALK, ROS1, and NTRK-targeted agents against treatment resistance and CNS metastases
- Utilize adverse event management strategies to optimize treatment efficacy and mitigate treatment risks
This on-demand webcast is available with synchronized slides and video/audio.
To be eligible for credit, participants must complete the educational activity, complete the 4-question post-test with a minimum score of 70%, and complete the activity evaluation form. Upon completing the activity, there will be instructions on how to complete the evaluation and print a certificate or other documentation of credit.
Release Date: January 20, 2023.
Expiration Date: January 20, 2024.
Estimated Time to Complete: 1.00 hour
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The faculty has reported the following:
Edward B. Garon: Advisory Board - ABL-Bio, AstraZeneca, Boehringer Ingelheim, Bristol Meyer Squibb, Eisai, Eli Lilly, EMD Serono, Gilead, GSK, Merck, Natera, Novartis, Personalis, Regeneron, Sanofi/Genzyme, Xilio, Zymeworks Biopharm; Grant/Research Support - ABL-Bio, AstraZeneca, Bristol Myer Squibb, Eli Lilly, EMD Serono, Genentech, Iovance, Merck, Mirati, Novartis
Corey J. Langer: Consultant - AstraZeneca; Grant/Research Support - Pfizer, Lilly, Advantagene, Inovio, Celgene, Vertex, Ariad (Takeda), Merck, Stemcentrex, Genentech/Roche, AstraZeneca, Trizell, GSK, Guardant; Other Material Support(Data Safety Monitoring) - Lilly, Amgen, Peregrine, Incyte, SWOG, Oncocyte; Advisory Board - Bristol Myers Squibb, Lilly, Pfizer, Synta, Boehringer-Ingelheim, AstraZeneca, Novartis, Abbott, Genentech/Roche, Savient, Bayer/Onyx, Celgene, Clarient, Clovis, Guardant, Merck, Gilead
Jessica J. Lin: Consultant - 14ner/Elevation Oncology, Bayer, Blueprint Medicines Corporation, C4 Therapeutics, Mirati Therapeutics, Novartis, Nuvalent, Pfizer, Turning Point Therapeutics; Grant/Research Support - 14ner/Elevation Oncology, Bayer, Genentech/Roche, Hengrui Therapeutics, Linnaeus Therapeutics, Loxo Oncology, Neon Therapeutics, Novartis, Nuvalent, Pfizer, Relay Therapeutics, Turning Point Therapeutics; Advisory Board - Genentech/Roche; Institutional Research Funding - 14ner/Elevation Oncology, Bayer, Linnaeus Therapeutics, Novartis, Nuvalent, Pfizer, Relay Therapeutics, Turning Point Therapeutics
Rajwanth Veluswamy: Advisory Board - AstraZeneca, BergenBio, Regeneron; Consultant - BeiGene; Grant/Research Support - AstraZeneca, Boerhinger Ingelheim, Bristol Myers Squibb, OncoNova; Speakers Bureau - AstraZeneca
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Supported by an independent educational grant from Turning Point Therapeutics.