Evolving Considerations for Therapeutic Drug Monitoring in IBD: Who, What, Why, When, and How?
Bruce E. Sands, MD, MS, FACG
Chief, Division of Gastroenterology
Icahn School of Medicine at Mount Sinai
New York, New York
Maria T. Abreu, MD
Director, Crohn's and Colitis Center, Professor of Medicine, Professor of Microbiology and Immunology
University of Miami Miller School of Medicine
Adam S. Cheifetz, MD
Director, Center for Inflammatory Bowel Disease
Beth Israel Deaconess Medical Center
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This educational activity is specifically designed for gastroenterologists, hospitalists, internal medicine specialists, and other health-care professionals (physicians-in-training, nurses, pharmacists, physician assistants, etc.) involved and/or interested in the therapeutic management of patients with IBD.
After participating in this activity, learners should be better able to:
- Assess the utility of TDM in evaluating serum biologic drug concentrations in patients struggling with PNR and secondary LOR to anti-TNF therapy
- Explain the differences between reactive and proactive TDM, including considerations for when to initiate each
- Evaluate currently available assays for precision-guided dosing and TDM in the management of IBD
To be eligible for credit, participants must complete the pre- and post-activity survey, view the recorded session, and complete the activity evaluation form. Upon completing the activity, there will be instructions on how to complete the evaluation and print a certificate or other documentation of credit.
Release Date: December 30, 2022
Expiration Date: December 20, 2023
Estimated Time to Complete: 1.0 hours
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UNAPPROVED AND/OR INVESTIGATIONAL USES OF DRUGS AND DEVICES
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The faculty has reported the following:
Bruce E. Sands, MD, MS, FACG:Consultant—AbbVie, Abivax, Amgen, AstraZeneca, Bacainn Therapeutics, Boehringer Ingelheim, Boston Pharmaceuticals, Bristol Myers Squibb, Calibr, Celltrion Healthcare, ClostraBio, Evommune, Galapagos, Genentech, GlaxoSmithKline, Gossamer Bio, Immunic, Index Pharmaceuticals, Innovation Pharmaceuticals, Janssen, Kaleido, Kallyope, Lilly, MiroBio, Morphic Therapeutic, Pfizer, Prometheus Bioscience, RedHill Biopharma, Surrozen, Takeda, Target RWE, Teva Biopharma, Ventyx Biosciences, Vivante Health; Advisory Board—Prometheus Bioscience; Grant/Research Support—Theravance Biopharma; Stockholder—Ventyx Biosciences, Vivante Health
Maria T. Abreu, MD: Consultant—AbbVie, Boehringer Ingelheim, Bristol Myers Squibb, Gilead, Janssen Pharmaceuticals, Landos Biopharma, Prometheus Laboratories, Takeda Pharmaceuticals, UCB; Speakers Bureau—HMP Education, Prometheus Laboratories
Adam S. Cheifetz, MD: Consultant—AbbVie, Arena, Bristol Myers Squibb, Grifols, Janssen, Pfizer, Prometheus Laboratories Inc., Samsung Bioepis, Takeda; Grant/Research Support—Inform Diagnostics
Susie Seaman, NP, MSN, CWCN, CWS (nurse planner)
Wound Clinic, Family Health Centers of San Diego
San Diego, California
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Supported by an independent educational grant from Prometheus Laboratories Inc.