This course closed on Monday, September 11, 2023

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Biomarker-Driven Treatment Approaches in Gastric Cancer: The Role of Gene Fusions and Molecular Profiling


Cathy Eng, MD, FACP, FASCO
David H. Johnson Endowed Chair in Surgical and Medical Oncology, Co-Director, GI Oncology, Co-Leader, Gastrointestinal Cancer Research Program
Vanderbilt-Ingram Cancer Center, MD Anderson Cancer Center
Nashville, Tennessee

David H. Ilson, MD, PhD
Professor of Medicine, Attending Physician, Member
Weill Cornell Medical College, Memorial Hospital, Memorial Sloan Kettering Cancer Center
New York, New York

Syma Iqbal, MD
Associate Professor of Clinical Medicine
USC Keck School of Medicine, Norris Comprehensive Cancer Center

Pashtoon M. Kasi, MD, MS
Director Colon Cancer Research; Director Liquid Biopsy Research
Weill Cornell Medicine/NewYork-Presbyterian; Englander Institute of Precision Medicine


Provided by HMP Education, an HMP Global Company.

For questions regarding this educational activity, or to cancel your account, please call 609-371-1137 or email


This activity is designed to meet the educational needs of those who are involved and/or interested in the treatment of patients with GI cancers, community oncologists, physicians, physician assistants, physicians-in-training, oncology nurses, and pharmacists.


After participating in this activity, learners should be better able to:

  • Assess the role of new and emerging biomarkers in gastric/GEJ cancer
  • Utilize biomarker testing and guideline recommendations for genomic profiling to inform diagnosis, prognosis, and treatment selection
  • Evaluate clinical efficacy and safety data of current and emerging targeted agents for the treatment of gastric/GEJ cancer
  • Apply adverse event management strategies and multidisciplinary care to mitigate treatment risks and maintain patient quality of life


To be eligible for credit, participants must complete the educational activity, complete the 6-question post-test with a score of 70% or better, and complete the evaluation form. Upon completing the activity, there will be instructions on how to complete the evaluation and print a certificate or other documentation of credit.

Release Date: September 12, 2022 
Expiration Date: September 11, 2023 
Estimated Time to Complete: 2 hours

There is no fee associated with this activity.


The evaluation is accessible after the activity via a PC or Mac computer with current versions of the following browsers: Mozilla Firefox, Google Chrome, or Safari. A PDF reader is required for print publications. 


In support of improving patient care, HMP Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


HMP Education designates this internet live/enduring activity for a maximum of 2.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


This internet live/enduring, knowledge-based activity (Universal Activity Number: UAN JA0006201-0000-22-151-H01-P) has been approved for a maximum of 2.00 contact hour (.200 CEUs).

The certificate is not the official record of your participation in the activity. The official record of credit will be the information in the CPE Monitor system. Following ACPE Policy, HMP Education must transmit your claim to CPE Monitor within 60 days from the date you complete this CPE activity. HMP Education is not able to report your claimed credit after this 60-day period. Eligibility for pharmacy credit is contingent upon the successful completion of a post-test and/or evaluation for each activity or session attended.


This continuing nursing education internet live/enduring activity awards 2.00 contact hour.

Provider approved by the California Board of Registered Nursing, Provider #13255 for 2.00 contact hour. 


American Academy of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 CreditTM from organizations accredited by the ACCME.


HMP Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with the AAPA CME Criteria. This internet live/enduring activity is designated for 2.00 AAPA Category 1 credit(s). Approval is valid until September 11, 2023. PAs should only claim credit commensurate with the extent of their participation.


This continuing medical education activity may include device or medicine brand names for participant clarity purposes only, due to the presence of different branded versions of the same product. No product promotion or recommendation should be inferred.


This activity may contain information about experimental and other uses of drugs or devices that are not currently approved by the European Medicines Agency (EMA) of the European Union or the Food and Drug Administration (FDA) of the United States. Participants are strongly encouraged to consult approved product labeling for any drug or device mentioned in this activity before use. The opinions expressed during this activity are the opinions of the respective authors, presenters or moderators and do not necessarily reflect the opinions of HMP Education.


The material presented and related discussions are not intended to be medical advice, and the presentation or discussion of such material is not intended to create and does not establish a provider-patient relationship. Medical advice of any nature should be sought from an individual’s own provider.

The opinions expressed in this educational activity are those of the faculty and are not attributable to HMP Global or any of its subsidiaries or affiliates. Clinical judgment must guide each professional in weighing the benefits of treatment against the risk of toxicity. Dosages, indications, and methods of use for products referred to in this activity are not necessarily the same as indicated in the package insert for each product, may reflect the clinical experience of the presenters, and may be derived from the professional literature or other clinical sources. Consult complete prescribing information before administering.


HMP Education is an independent provider of continuing medical education. HMP Education has no proprietary or financial interest in medical or healthcare products over which the FDA (USA) or EMA (EU) has regulatory authority.

In accordance with our disclosure policies, HMP Education is committed to ensuring balance, independence, objectivity, and scientific rigor for all accredited continuing education. These policies include assigning relevance to, and mitigating, all perceived or real conflicts of interest between any individual with control over the content and any ineligible company (commercial interest) as defined by the ACCME.

Any individual with control over accredited content, including planner, faculty, and reviewer, is required to globally disclose:

  1. Individual relationship(s) or lack thereof, and its nature, with any/all ineligible company, and;
  2. Any investigational, off-label, or non-FDA approved content or discussion

HMP Education has reviewed these disclosures, assigned relevance based on the relationship and scope of content, and identified those with the potential to compromise the goals and educational integrity of the education. Relevant relationships, or lack thereof, are shared with the learner.

Education has been independently peer-reviewed to validate content, mitigate identified conflicts of interest, and ensure:

  1. All recommendations involving clinical medicine is based on evidence that is accepted within the medical profession as adequate justification for their indications and contraindications in the care of patients.
  2. All scientific research referred to, reported, or used in accredited continuing education in support or justification of a patient care recommendation conforms to the generally accepted standards of experimental design, data collection, and analysis.
  3. Content is appropriate, fair and balanced, unbiased, referenced, and non-promotional.

All relevant financial relationships have been mitigated.


The faculty has reported the following:

Dr. Eng: Advisory Board - Bayer, Boston Scientific, GSK, Halio Dx, Merck, J&J, Natera, Taiho; Other Financial or Material Support - Elevar, Hutchinson, Merck, Pfizer

Dr. Ilson: Advisory Board - Amgen, Astellas, Bayer, Genentech, Novartis, Roche/Genentech, Taiho Pharmaceutical; Consultant - Astellas, AstraZeneca, Bristol Myers Squibb, Eli-Lilly, Genentech, Merck, Novartis, Roche/Genentech, Taiho Pharmaceutical; Research Support - Bayer, Genentech

Dr. Kasi: Grant/Research Support - Amgen, AstraZeneca, Boston Scientific, Seagen, TerSera; Advisory Board - Bayer, Daiichi Sankyo, Delcath Systems, Eisai, Eli Lilly, Exact Sciences, Foundation Medicine, Incyte, Merck MSD, Natera, QED Therapeutics, Servier, Taiho, Tempus Health; Consultant - Bayer, Daiichi Sankyo, Eisai, Eli Lilly, Exact Sciences, Foundation Medicine, Incyte, Merck MSD, Natera, QED Therapeutics, Servier, Taiho, Tempus Health; Other Financial or Material Support, Travel Funds, Trial Support to Institution - AstraZeneca

Dr. Iqbal: Advisory Board - AstraZeneca, Bristol-Myers Squibb, Daiichi Sankyo; Consultant - Merck


HMP Education planners and staff include Samantha Conforti, Kelly Jackson, Paul O'Neil, Randy Robbin, Manjusha Sala, and Andrea Zimmerman.

No HMP Education planner or staff has disclosed a relevant financial relationship with any ineligible company (commercial interest).


HMP Education complies with the legal requirements of the Americans with Disabilities Act and the rules and regulations thereof. If any participant in this educational activity needs accommodations, please call 609-371-1137.


HMP Education protects the privacy of personal and other information regarding participants, educational partners, and joint providers. HMP Education and our joint providers will not release personally identifiable information to a third party without the individual’s consent, except such information as is required for reporting purposes to the appropriate accrediting agency. HMP Education maintains physical, electronic, and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Copyright © 2022 by HMP Education. All rights reserved. No part of this accredited continuing education activity may be reproduced or transmitted in any form or by any means, electronic or mechanical, without first obtaining permission from HMP Education.


Any participant wanting to file a grievance with respect to any aspect of a continuing education activity accredited by HMP Education may contact Samantha Conforti, Senior Manager, Accreditation and Compliance, by phone at 609-371-1137, by email at or in writing at 104 Windsor Center Drive, East Windsor, NJ 08520. Ms. Conforti will review the grievance and respond within 30 days of receiving the complaint.


Supported by an independent educational grant from Astellas.