Pre-Test Navigating Patient Selection to Optimize the Clinical and Economic Effectiveness of Skin Substitutes Pre-Test Real-world evidence can be generated by different study designs, including _________. Prospective observational studies Retrospective observational studies Randomized trials All of the above Which layer of bilayered living cellular construct contains living fibroblasts that proliferate and produce human collagen and other ECM proteins, growth factors, and cytokines? Epidermal layer Dermal layer In patients with DFUs, increased baseline ulcer size and duration do not significantly impact rates of complete healing. True False In qualitative studies, patients expressed _________. Confidence in changing their own dressings Fear of touching their wounds
