Pre-Test The Evolving Role of Topical PDE-4 Inhibitors for the Management of Immune-Mediated Inflammatory Skin Conditions Pre-Test Which of the following statements regarding management of IMISCs is TRUE? Conventional topical agents are associated with durable safety and long-term efficacy Patient adherence to topical therapy is generally higher than adherence to oral therapy Patients on topical treatments require fewer follow-up visits than patients on systemic therapies Prolonged use of conventional topical agents is associated with poor patient satisfaction Unsure PDE-4 inhibitors target which of the following mechanisms involved in IMISC pathogenesis? cAMP degradation IL-17 production NF-kB activation TNFα elevation Unsure Which of the following non-steroidal topical agents was shown in the DERMIS-1 and -2 phase 3 trials to be highly effective in treating plaque psoriasis in intertriginous areas? Crisaborole Difamilast Roflumilast Tazarotene Unsure How confident are you in your ability to identify patients who may benefit from treatment with topical PDE-4 inhibitors? Very Confident Confident Somewhat confident Not very confident Not at all confident
